Faculty: Division of Nephrology and Hypertension
Faculty of the Division of Nephrology and Hypertension conduct research and treat people with kidney diseases of various types, such as glomerular diseases, chronic kidney disease, kidney stones, diabetes, high blood pressure, and other kidney diseases.
To learn more about our faculty, follow the links below to access their Georgetown University faculty profiles. If a particular faculty member doesn’t have a link, their profile is currently under development and will be available shortly.
Also within the division, faculty of the Center for Hypertension, Kidney & Vascular Research investigate the mechanisms that underlie kidney and vascular (blood vessel) diseases, high blood pressure (hypertension), and train the next generation of leaders in these fields.
Chief of Nephrology and Hypertension
Fellowship Program Director
- Medical Degree: Johns Hopkins University School of Medicine, 1987
- Internship: Johns Hopkins Hospital, 1987
- Residency: Johns Hopkins Hospital, 1988-90
- Fellowship: University of Pennsylvania, 1990-94
- Certifications: Internal Medicine, 1990; Nephrology, 1992
Dr. Choi is the Chief and Program Director of the MedStar Georgetown Hospital Nephrology and Hypertension Division joining Georgetown in 2019. He is the immediate Past-President of the National Kidney Foundation (NKF), and won the Garabed Eknoyan Award for his outstanding contributions to the NKF.
He has been recognized as a clinician educator in nephrology by multiple organizations. He was appointed the first Chair of the NKF Education Committee and also was Chair of the NKF Spring Clinical Meeting in 2011. He is on the American Board of Internal Medicine Nephrology Test Writing Committee. He has served on the American Society of Nephrology (ASN) Post-Graduate Education Committee and spoken internationally for ASN Highlights in Clinical Nephrology. He was also the Co-editor of the Nephrology Self-Assessment Program (NephSAP) for Chronic Kidney Disease and Progression. Prior to joining Georgetown, he was the Nephrology Clinical Director and Fellowship Program Director at Johns Hopkins where he won multiple teaching awards voted on by medical students, housestaff, and the University.
He is on the editorial board of the American Journal of Kidney Diseases and BMC Nephrology. He had been Deputy Editor of Advances in Chronic Kidney Disease and was on the editorial board for the Clinical Journal of the American Society of Nephrology. He is Chair of the Mid-Atlantic Nephrology Young Investigators Forum. His clinical and research interests include glomerular diseases, chronic kidney disease, kidney stones and medical education.
- Choi MJ, Fernandez PC, Patnaik A, Coupaye-Gerard B, D’Andrea D, Szerlip H, Kleyman TR. Brief Report: Trimethoprim induced hyperkalemia in a patient with AIDS. N Engl J Med. 1993 Mar 11;328(10):703-6. PubMed PMID 8433730.
- King LS, Choi M, Fernandez PC, Cartran JP, Agre P. Brief Report: Urinary concentrating defect in aquaporin-1 null individuals. N Engl J Med. 2001;345:175-179. PubMed PMID 11463012.
- Choi MJ, Eustace JA, Gimenez LF, Atta MG, Scheel PJ, Sothinathan R, Briggs WA. Mycophenolate mofetil treatment for primary glomerular diseases. Kidney Int. 2002 Mar;61(3):1098-114. PubMed PMID 11849465.
- Berliner AR, Haas MA, Choi MJ. Sarcoidosis: the nephrologist’s perspective. Am J Kidney Dis. 2006 Nov;48(5):856-70. PubMed PMID: 17060009.
- Choi MJ, Ziyadeh FN. The Utility of the Transtubular Potassium Gradient in the Evaluation of Hyperkalemia. J Am Soc Nephrol. 2008 Mar;19(3):424-6. PubMed PMID: 18216310.
- Trachtman H, Choi MJ, Somers M, Mariani L, Beck L, Waldman M, Langford C, Bomback A, Holzman L. KDOQI US Commentary on the 2012 KDIGO clinical practice guideline for glomerulonephritis. Am J Kidney Dis. 2013;62:403-41. (corresponding author)
- Parsa A, Kao WH, Xie D, Astor BC, Li M, Hsu CY, Feldman HI, Parekh RS, Kusek JW, Greene TH, Fink JC, Anderson AH, Choi MJ, Wright JT Jr, Lash JP, Freedman BI, Ojo A, Winkler CA, Raj DS, Kopp JB, He J, Jensvold NG, Tao K, Lipkowitz MS, Appel LJ; AASK Study Investigators; CRIC Study Investigators. APOL1 risk variants, race, and progression of chronic kidney disease. N Engl J Med. 2013 Dec 5;369(23):2183-96. PubMed PMID 24206458.
- Chen TK, Choi MJ, Kao WH, Astor BC, Scialla JJ, Appel LA, Li L, Lipkowitz MS, Wolf M, Parekh RS, Winkler CA, Estrella ME, Crews DC. Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression. Clin J Am Soc Nephrol. 2015 Dec 7;10(12):2128-35. PubMed PMID 26430087.
- Subramaniam RM, Suarez-Cuervo C, Wilson RF, Turban S, Zhang A, Sherrod C, Aboagye J, Eng J, Choi MJ, Hutfless S, Bass EB. Effectiveness of Prevention Strategies for Contrast –Induced Nephropathy: A Systematic Review and Meta-analysis. Ann Intern Med. 2016 March 15;164(6):406-16. doi: 10.7326/M15-1456. PubMed PMID 26830221.
- Greer RC, Liu Y, Cavanaugh K, Diamantidis CJ, Estrella MM, Sperati CJ, Soman S, Abdel-Kader K, Agrawal V, Plantinga LC, Schell JO, Simon JF, Vassalotti JA, Jaar BG, Choi MJ; National Kidney Foundation Education Committee. Primary Care Physicians’ Perceived Barriers to Nephrology Referral and Co-management of Patients with CKD: a Qualitative Study. J Gen Intern Med. 2019 Jul;34(7):1228-1235. Epub 2019 Apr 16. PubMed PMID: 30993634.
- Thavarajah S, Choi MJ. The Use of Erythropoiesis-Stimulating Agents in Patients with CKD and Cancer: A Clinical Approach. Am J Kidney Dis. 2019 Aug 5. pii: S0272-6386(19)30767-X. [Epub ahead of print] PubMed PMID:31395400.
- Gordon-Cappitelli J, Choi MJ. Prophylactic Anticoagulation in Adult Patients with Nephrotic Syndrome. Clin J Am Soc Nephrol. 2020 Jan;15 (1):123-125. PubMed PMID: 31575616.
- Agarwal V, Plantinga L, Abdel-Kader K, Pivert K, Provenzano A, Soman S, Choi MJ, Jaar BG. Burnout and Emotional Well-Being among Nephrology Fellows: A National Online Survey. J Am Soc Nephrol. 2020 Apr;31(4):675-685. PubMed PMID 32123052.
Professor of Nephrology
- Medical Degree: Oxford University, UK, 1969
- Ph.D: London University, UK, 1974
- Internship: London University, UK, 1970
- Residency: London University, UK, 1971
- Fellowship: London University, UK, 1973
- Certifications: Internal Medicine, 1986; Nephrology, 1992; Certified Hypertension Specialist, 1999
Dr. Wilcox is the former Chief of the Georgetown Nephrology Division and the George E. Schreiner Professor of Nephrology. He previously held professional positions at University of Florida, Harvard Medical School, Yale Medical School, University of Cambridge, and London University. He holds an NIH individual investigator RO-1 grant and an NIH Small Business Investigator Research and Development Grant. He has been Chair of several NIH/NIDDK Study Sections, and was the Chair of the AHA Council of High Blood Pressure Research. He has received many national and international honors and distinguished lecturer positions. He is a mentor for many faculty and fellows of the Georgetown Nephrology and Hypertension Division. He has been elected a Fellow of the Royal Society of Medicine (UK), a Fellow of the Royal College of Physicians (UK), a Master of the American College of Physicians, a Fellow of the American Society of Nephrology and a Fellow of the American Heart Association Councils on Hypertension and the Kidney in Cardiovascular Disease.
His research is focused on the interaction between blood pressure and the kidney. His basic research entails studies of genes, cells, tissues and animal models. Currently, he is investigating the hypothesis that oxidative stress is a proximate cause of most of the diseases of the second half of life. He studies this in animal models of hypertension, kidney disease, menopause and aging using a combination of methods including isolated, perfused renal afferent, mesenteric and intracerebral arterioles from mice, and long term whole animal studies. He has developed new catalytic long-acting drugs to combat oxidative stress and validated them in his rat and mouse models. His clinical/translated research is focused on better methods to manage the complications of chronic kidney disease and hypertension. He investigates small human arterioles dissected from a skin biopsy to study the origin of vascular disease. He has developed a non-invasive vascular function laboratory with state-of-the-art equipment to study small and large vessel function in human subjects. His present research includes enhancement of host-defense against COVID-19 by mineralocorticosteroid receptor antagonists and the underlying cause of microvascular dysfunction in COVID-19 survivors. He is developing a new extended release formulation of a diuretic that he has taken through Phase 1 clinical trials in normal subjects. He has published over 350 papers and two books.
- Shah, S., Pitt, B., Brater, D.C, Feig, P.U., Shen, W., Khwaja, F.S. Wilcox, C.S.: Sodium and fluid excretion with torsemide in healthy subjects is limited by the short duration of diuretic action. J Am Heart Assoc, Oct 5, 6 pii:e006135 doi: 10.1161/jJAHA 117.006135, 2017 (PMCID: PMC5721837),
- Wilcox, C.S.: Antihypertensive and Renal Mechanisms of SGLT2 (Sodium-Glucose Linked Transporter 2) Inhibitors. Hypertension, 2020 Apr 75(4):894-901 (PMID: 32114848).
- Wilcox, C.S., Pathogenesis of Hypertension. In Gilbert, S.J. and Weiner, D.E. (eds): “National Kidney Foundation Primer on Kidney Disease, 7th Edition. Elsevier, Philadelphia PA, Chapter 64, 2017.
- Lipkowitz M.S., Wilcox C.S.: Dietary salt intake for patients with hypertension or kidney disease. In Ikizler T.A. and Mitch W.E. (eds): “Handbook of Nutrition and the Kidney”, 7th Edition. Wolters Kluwer, Philadelphia PA, Chapter 17, 2018.
- Hoorn, E.J., Wilcox, C.S., Ellison, D.H., Diuretics. In Brenner, B.M., Rector, F.C. (eds): “Brenner & Rector’s The Kidney”, 11th edition. Elsevier, Philadelphia PA, in press, 2018.
Associate Professor of Medicine
- Medical Degree: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 1997
- Internship: Yale University School of Medicine, Danbury Hospital, Danbury, CT, 2002
- Residency: Yale University School of Medicine, Danbury Hospital, Danbury, CT, 2004
- Fellowship: Columbia University College of Physicians and Surgeons, St Luke’s Roosevelt Hospital Center, New York, NY, 2006
Dr. Dragoi is currently an Associate Professor of Medicine. He has been on our faculty since 2008. Prior to joining our faculty, he was an Assistant Professor of Medicine at the University of Missouri – Columbia where he worked with pioneers in the development of peritoneal and home dialysis (Karl Nolph, Zyblut Twardowski and Ramesh Khanna). At Georgetown he had been Medical Director of Home Dialysis, and helped successfully create and grow Washington’s first and only Home-only Dialysis Center: DaVita Georgetown Home Training Program. He is presently a Medical Director of the Grant Park Hemodialysis unit. His clinical interests include peritoneal dialysis, home hemodialysis, novel renal replacement techniques, recurrent nephrolithiasis and ANCA vasculitis. Dr. Dragoi is active in training other physicians and health professionals in the broad field of Nephrology with emphasis on successful patient recruitment and management of home dialysis centers.
- Li T, Wilcox CS, Lipkowitz MS, Gordon-Cappitelli J, Dragoi S: Rationale and Strategies for Preserving Residual Kidney Function in Dialysis Patients. Am J Nephrol 2019;50(6):411-421. doi:10.1159/000503805
- Nader MA, Aguilar R, Sharma P, Krishnamoorthy P, Dragoi S, Gordon J, Shen W, Nilubol C, Li P, Lipkowitz M: In-Hospital Mortality in Cirrhotic Patients with End-Stage Renal Disease Treated with Hemodialysis versus Peritoneal Dialysis: A Nationwide Study. JPerit Dial Int 2016. doi:10.3747/pdi.2016.00131
- Imam, N., Khouzam, N., Rahmat, U., Rashidi, A., Zuccato, M., Nilubol, C. and Dragoi, S., 2012. Falsely Elevated Whole-Blood Tacrolimus Levels in a Kidney Transplant Patient. Am J Kidney Dis, 59(4), pp.A1-A92
Assistant Professor of Medicine
- Medical Degree: Temple University School of Medicine, Philadelphia PA, 2005
- Internship: Temple University School of Medicine, Philadelphia PA, 2005-2006
- Residency: Temple University School of Medicine, Philadelphia PA, 2006-2008
- Fellowship: Johns Hopkins University School of Medicine, Baltimore, MD 2009-2011
- Certification: Internal Medicine 2008, Nephrology 2011
Dr. Gordon-Cappitelli completed her nephrology fellowship at the Johns Hopkins University School of Medicine, where she was an instructor prior to joining Georgetown in 2012. She has been involved in teaching fellows, residents and students and has taught at the Mid-Atlantic Fellows Forum. She has helped revise our Nephrology Fellowship curriculum and has previously served as Associate Fellowship Director.
Her clinical interests include home dialysis modalities, management of chronic kidney disease, hypertension, nephrolithiasis, glomerular diseases and pregnancy related hypertension and renal disease. She is Medical Director of the Georgetown Home Dialysis Unit, and is an avid supporter of home dialysis modalities. She is the physician representative for Peritoneal Dialysis at Medstar Georgetown University Hospital.
- Judit Gordon-Cappitelli and Michael J Choi. Prophylactic Anticoagulation in Adult Patients with Nephrotic Syndrome. CJASN 2019. 15 (1) 123-125.
- Tian Li, Christopher S. Wilcox, Michael S. Lipkowitz, Judit Gordon-Cappitelli, Serban Dragoi. Rationale and Strategies for Preserving Residual Kidney Function in Dialysis Patients. American Journal of Nephrology. 2019; 50: 411-421.
- Nader MA1, Aguilar R2, Sharma P3, Krishnamoorthy P4, Serban D2, Gordon-Cappitelli J2, Shen W2, Nilubol C2, Li P5, Lipkowitz M2 In-Hospital Mortality in Cirrhotic Patients with End-Stage Renal Disease Treated with Hemodialysis Versus Peritoneal Dialysis: A Nationwide Study. Perit Dial Int. 2017 Jul-Aug;37(4):464-471.
- Gordon J, Kopp JB. Off the beaten renin-angiotensin-aldosterone system pathway: new perspectives on antiproteinuric therapy. Adv Chronic Kidney Dis. 2011 Jul;18(4):300-11.
Assistant Professor of Medicine
- Medical Degree: Chulalongkorn University Faculty of Medicine, Bangkok, Thailand 1999
- Internship: St Elizabeth Health Center, Northeastern Ohio Universities College of Medicine (NEOUCOM) 2002
- Residency: St Elizabeth Health Center, Northeastern Ohio Universities College of Medicine (NEOUCOM) 2004
- Fellowship: University of Wisconsin School of Medicine and Public Health, Madison, WI 2007
- Fellowship: Columbia University Medical Center, New York, NY 2009 (Transplant Nephrology)
Dr Nilubol is currently an Assistant Professor of Medicine. She has been on our faculty since 2010. Prior to joining our faculty, she was on faculty at Columbia University Medical Center and SUNY Downstate Medical Center in New York. Since joining our faculty, she has had many active roles in fellowship education as well as medical student education. She has directed fellows’ Clinical Conference Series incorporating weekly board review questions. She also co-directs he Nephrology Transplant lecture series where fellows as well as the rest of transplant team members attend. She is a Nephrology Elective Course Director for 4th year medical students and has worked to enhance their experience and exposure in the field of kidney disease. She has given didactic lectures to Georgetown medical students. She was accepted into the Leadership Education and Development (LEAD) program which is part of the nationwide educational leadership development program administered through the collaboration of Association of American Medical College (AAMC), Georgetown University Medical Center and MedStar Health. She serves on the National Kidney Foundation (National Capital Area & Virginia) Medical Advisory Board and is a Chair of a research subcommittee. She is a member of the Georgetown-MedStar Institutional Review Board (IRB).
Her special interests are in renal replacement modality education, long-term care for kidney transplant recipients and home dialysis patients. With her broad expertise across different modalities, her active goal currently is towards founding Kidney Disease Patient Education Program.
- Immune Checkpoint Inhibitor-induced Fanconi Syndrome. Farid S, Latif H, Nilubol C, Kim C.Farid S, et al. Cureus. 2020 Apr 16;12(4):e7686. PMID: 32431966
- In-Hospital Mortality in Cirrhotic Patients with End-Stage Renal Disease Treated with Hemodialysis Versus Peritoneal Dialysis: A Nationwide Study. Nader MA, Aguilar R, Sharma P, Krishnamoorthy P, Serban D, Gordon-Cappitelli J, Shen W, Nilubol C, Li P, Lipkowitz M.Nader MA, et al. Perit Dial Int. 2017 Jul-Aug;37(4):464-471. doi: 10.3747/pdi.2016.00131. Epub 2017. PMID: 28348101
- Preemptive kidney transplantation in systemic lupus erythematosus. Naveed A, Nilubol C, Melancon JK, Girlanda R, Johnson L, Javaid B.Naveed A, et al. Among authors: Nilubol C. Transplant Proc. 2011 Dec;43(10):3713-4. doi: 10.1016/j.transproceed.2011.08.092.Transplant Proc. 2011. PMID: 22172832
- Smavatkul C [Nilubol C], Pascual J, Desai AG, Samaniego M, Becker BN, Djamali A. Disease progression and outcomes in type 1 diabetic kidney transplant recipients based on posttransplantation CKD staging. Am J Kidney Dis. 2007 Oct;50(4):631-40. PMID 17900463
- Djamali A, Sadowski EA, Muehrer RJ, Reese S, Smavatkul C [Nilubol C], Vidyasagar A, Fain SB, Lipscomb RC, Hullett DH, Samaniego-Picota M, Grist TM, Becker BN. BOLD-MRI assessment of intrarenal oxygenation and oxidative stress in patients with chronic kidney allograft dysfunction. Am J Physiol Renal Physiol. 2007 Feb;292(2): F513-22. Epub 2006 Oct 24. PMID: 17062846
- Longstreth KL, Robbins SD, Smavatkul C [Nilubol C], Doe NS. Cephalexin-induced acute tubular necrosis. Pharmacotherapy. 2004 Jun;24(6):808-11. PMID: 15222673
Associate Professor of Medicine
- Medical Degree: MD and PhD, Fudan University Shanghai Medical College, 2001
- Internship: Yale University Bridgeport Hospital, 2007
- Residency: Yale University Bridgeport Hospital, 2009
- Fellowship: Harvard University Beth Israel Deaconess Medical Center, 2012
Dr. Shen joined Georgetown as a faculty member in 2012 after she completed her nephrology fellowship training. Currently she is an associate professor and the medical director of Davita Rivertowne Dialysis Unit. During her fellowship, she was chosen to be one of the tutorial leaders for the Harvard Medical School Renal Pathophysiology Tutorial in two consecutive years. She received wonderful feedback from the HMS students for her teaching.
She is interested in clinical and translational research. Her interest in understanding the mechanisms of proteinuria and developing new therapies for patients with proteinuric CKD has led her to involve in a clinical trial and a translational research project. She is also the principle investigator of an epidemiology study to compare the AKI incidence between different coronary revascularization interventions by using a national database. She has received the grants from the Center for Hypertension, Kidney and Vascular Research and Department of Medicine for her epidemiology study and clinical trial.
Dr. Shen has mentored multiple medical residents, nephrology fellows and medical students to conduct clinical research at Georgetown. The research results have been published in peer-reviewed journals, presented at national and regional conferences by the trainees. Two of the residents she mentored have won American Society of Nephrology Kidney Stars Award.
She served as a grant reviewer for D-CFAR Research Award Program, and National Kidney Foundation Joseph M. Krainin, M.D. Memorial Young Investigator Award. She also has served as a reviewer for several nephrology or medicine journals. She served as a committee member for Georgetown University Biomedical Institutional Review Board. She also oversaw medical student’s scholarly activities by serving as a member of Independent Scholarly Project Oversight Committee.
- Wilcox CS, Shen W, Liu X, Kasichayanula S, Bui A, Boulton DW, Leslie BR, Griffen SC. Interaction between the SGL2 inhibitor dapagliflozin and the loop diuretic bumetanide in normal human subjects. J Am Heart Assoc. 2018;7: e007046. doi: 10.1161/JAHA.117.007046
- Shen W, Campos RA, Montero AR, Fernandez SJ, Taylor AJ, Wilcox CS, Lipkowitz MS, Umans JG. Acute kidney injury and in-hospital mortality after coronary artery bypass graft versus percutaneous coronary intervention—experience from the National Inpatient Sample. Am J Nephrol 2017;45:217-225. DOI:10.1159/000455906
- Nader MA, Aguilar CR, Sharma P, Krishnamoorthy P, Serban D, Gordon-Cappitelli J, Shen W, Nilubol C, Li P, Lipkowitz M. In-hospital Mortality in Cirrhotic patients with End Stage Renal disease treated with Hemodialysis versus Peritoneal dialysis: A Nationwide Study. Perit Dial Int 2017; Mar 27. DOI: 10.3747/pdi.2016.00131
- Shah S, Pitt B, Brater C, Feig, P, Shen W, Wilcox C.S. An extended release formulation of torsemide enhances sodium and fluid loss in healthy subjects. J Am Heart Assoc. 2017; 6:e006135
Robert Rubin, MD
Distinguished Professor of Medicine
- Medical Degree: Cornell University Medical College, 1970
- Internship: New England Medical Center Hospital, Boston, Intern, 1971
- Residency: New England Medical Center Hospital, Boston, 1972
- Fellowship: New England Medical Center Hospital, Boston, 1974-1976
Dr. Rubin is currently Distinguished Professor of Medicine. He has been on our faculty since 1981. Prior to joining our faculty, he founded the Hypertension Clinic at the New England Medical Center and served as Chief of Nephrology at the Lemuel Shattuck Hospital in Boston. From 1981-1984 he was appointed by President Reagan as Assistant Secretary of Planning and Evaluation at the Department of Health and Human Services (DHHS) as well as an Assistant Surgeon General. He has been the President and CEO of an international health care consulting company (The Lewin Group) and medical director of a pharmacy benefits management company. Dr. Rubin was the founding editor of the Public Policy section of the Clinal Journal of the American Society of Nephrology.
In addition, he has served on several committees of the Nation Academy of Medicine (formerly the Institute of Medicine). Most recently on the Committee on Strategies to Reduce Sodium Intake. Dr. Rubin was a trustee of the American Kidney Fund for 17 years and currently serves on their Clinical Scientist in Nephrology grant selection committee. He was co-chair of the DHHS committee that designed the ESRD prospective payment system .He has served on numerous public and non-profit advisory boards including the Robert Wood Johnson Health Policy Fellowships (13 years), the Leonard Davis Institute, the John F. Kennedy School of Government, the Institute of Health Technology Studies (chair of research committee)
His special interests include Outcomes Research, Pharmacoeconomics, Health Care Policy and Hypertension. He chairs our bi-monthly journal club meetings and curates our weekly Article of the Week series for faculty and Fellows.
- Rubin RJ. A Tribute to George E. Schreiner. Clin J Am Soc Nephrol 7: 1353-1354, 2012.
- Rubin RJ. Effect of the 2012 Election on Health Policy Issues for the Nephrologist. Clin J Am Soc Nephrol 8: 336-338, 2013.
- Brunelli SM, Monda KL, Burkhart JM, Gitlin M, Neumann PJ, Park GS, Symonian-Silver M, Yue S, Bradbury BD, Rubin RJ. Early Trends From the Study to Evaluate the Prospective payment System Impact on Small Dialysis Organizations (STEPPS). Am J Kidney Dis 61(6):947-956, 2013.
- Rubin, RJ. Understanding Washington: A Nephrologist’s Perspective From Inside the Beltway. Am J Kidney Dis 62 (6):1042–1045, 2013.
- Monda KL, Joseph P, Neumann PJ, Bradbury BD, Rubin RJ. Comparative changes in treatment practices and clinical outcomes following implementation of a prospective payment system: the STEPPS study. BMC Nephrology, 16:67 (01 May) 2015.
- Wish JB, Charytan C, Chertow GM, Kalantar-Zadeh K, Kliger AS, Rubin RJ, Yee J, Fishbane S. Introduction of Biosimilar Therapeutics Into Nephrology Practice in the United States: Report of a Scientific Workshop Sponsored by the National Kidney Foundation. Am J Kidney Dis. 68(6):843-852, 2016
- Campbell, JD, Belozeroff, V, Wittington, MD, Rubin, RJ, Raggi, P, Briggs, AH Prices for common cardiovascular drugs in the US are not aligned with value. Health Affairs, 37 1298-1305 2018, DOI: 10.1377/hlthaff.2018.0221
- Fuller, DS, Xing, S, Belozeroff, V, Yehoshua, A, Morgenstern, H, Robinson, BM, Rubin, RJ, Bhatt, N, Pisoni, RL, Variability in Cinacalcet Prescription across US Hemodialysis Facilities, CJASN, 14 (2) 241-249 2019; DOI: https://doi.org/10.2215/CJN.09550818
Keiko Greenberg, MD
Assistant Professor of Medicine
Associate Program Director, Nephrology Fellowship
- Medical Degree: University of Virginia School of Medicine, 2009
- Internship: Johns Hopkins Hospital, 2010
- Residency: Johns Hopkins Hospital, 2012
- Fellowship: Johns Hopkins Hospital, 2015
- Certifications: Internal Medicine 2012; Nephrology 2015
Dr. Greenberg is currently Assistant Professor of Medicine. She has been on our faculty since 2020. Prior to joining our faculty, she was a faculty member in the Division of Nephrology at the Johns Hopkins University School of Medicine. There, she was the medical director for home hemodialysis and was involved in research in end-stage kidney disease. She also received a Master of Health Science degree in Clinical Epidemiology from the Johns Hopkins Bloomberg School of Public Health in 2015. She is recognized for education and currently is serving as a member of the National Kidney Foundation CME Review Committee and has been invited to write for the American Journal of Kidney Diseases core Curriculum series. She is our new Associate Program Director in Nephrology and is helping grow hour social media presence. Her clinical interests include chronic kidney disease, end-stage kidney disease, home dialysis, nephrolithiasis, and patient education.
- Greenberg KI, McAdams-DeMarco MA, Köttgen A, Appel LJ, Coresh J, Grams ME. Plasma Urate and Risk of a Hospital Stay with AKI: The Atherosclerosis Risk in Communities Study. Clin J Am Soc Nephrol. 2015 May 7;10(5):776-83.
- Greenberg KI, Perazella MA, Atta MG. HIV and HCV Medications in End-Stage Renal Disease. Semin Dial. 2015 Jul-Aug;28(4):397-403.
- Shah S, Jaggi K, Greenberg K, Geetha D. Immunoglobulin levels and infection risk with rituximab induction for anti-neutrophil cytoplasmic antibody-associated vasculitis. Clin Kidney J. 2017 Aug; 10(4): 470–474.
- Greenberg KI, Jaar BG. Urgent start peritoneal dialysis: are we there yet? BMC Nephrol. 2020 Jan;21(1):39.
Transplant Nephrology Faculty
Associate Professor of Medicine
- Medical Degree: University of Debrecen Medical School, 2002
- Internship: Michael Reese Hospital, 2003-2004
- Residency: University of Connecticut Primary Care Program, 2004-2007
- Chief Medical Resident: University of Connecticut Primary Care Program, 20007-2008
- Nephrology Fellowship: University of Connecticut, 2008-2010
- Transplant Nephrology Fellowship: Medical University of South Carolina 2010-2011
Dr. Thomas is an Associate Professor in the Department of Medicine. He joined the faculty in 2018 and his primary clinical duties are with the MedStar Georgetown Transplant Institute. After he completed his transplant nephrology fellowship at the Medical University of South Carolina (MUSC) he would remain on as faculty. While at MUSC he was the transplant fellowship director and the interim medical director of the kidney transplant program. He would move onto the University of Maryland Medical Center where he received the Nephrology Teacher of the Year award in his first year there and subsequently would be the associate nephrology fellowship director.
His interests in transplantation includes living donor donation, the use of hepatitis C positive organs, the management of post-transplant complications, use of telemedicine, and increasing access to transplantation. He has written several papers and chapters pertaining to transplantation. Dr. Thomas is passionate about medical education and the use of social media to educate and garner interest in nephrology. To this end he completed the Nephrology Social Media Collaborative (NSMC) Internship and is currently a faculty member. He has written blog posts, produced visual abstracts, moderated the Twitter Nephrology Journal Club (NephJC), and more locally has done several events using social media for patient education. He is also an Associate member of the GUMC Teaching Academy. Dr. Thomas is involved with the National Kidney Foundation (NKF) as he is a presenter at the annual Mid-Atlantic NKF First Year Fellows Symposium, member of the NKF CME Committee, and on the District of Columbia NKF Board.
Dr. Thomas is a staunch supporter of mentorship and diversity in medicine. He completed the Cura Personalis fellowship at the Georgetown Medical School and is the mentor for group of medical students throughout their four years of medical school. He also works with medical students as a volunteer for the Hoya Clinic which provides free medical care for the underserved population in the District of Columbia. In regards to diversity, he is involved with the Department of Medicine’s efforts on diversity and is a Bias Reduction and Improvement Coach presenting on issues such as implicit bias and microaggressions in the workplace.
- Jahoty, A., Madariaga, HM, Thomas, B, Lerma EV. Hepatitis C in Chronic Kidney Disease. Accepted for publication by Disease-a-Month 5/25/20
- Ramaswamy K, Madariaga HM, Thomas B, Lerma EV. Kidney Transplantation for the Primary Care Provider. Dis Mon. 2019 Aug 13 doi: 10.1016/j.disamonth.2019.07.002 PMID: 31420084
- Thomas B, Madariaga H, Lerma Edgar. Kindey-Pancreas Transplantation. Medscape. 2018 May 16
- Thomas B, Lerma Edgar. Proteinuria. Medscape. 2018 April 28
- Thomas B, Weir M. The Evaluation and Therapeutic Management of Hypertension in the Transplant Patient. Curr Cardiol Rep. 2015 Nov;17(11):95. doi: 10.1007/s11886-015-0647-z. Review. PMID: 26362301
- Thomas B, Weir M. “Epidemiology and Outcomes in Kidney Transplantation.” Nephrology Secrets 4th Edition Rockville: Elsevier, 2018: 393-398
- Thomas B, Weir M. “Donor and Recipient Evaluation.” Nephrology Secrets 4th Edition Rockville: Elsevier, 2018: 399-404
- Thomas B, Weir M. “Immunosuppression.” Nephrology Secrets 4th Edition Rockville: Elsevier, 2018: 405-409
- Thomas B, Weir M. “Rejection of Renal Transplant.” Nephrology Secrets 4th Edition Rockville: Elsevier, 2018: 410-414
- Thomas B, Weir M. “Post-Transplantation Malignancies.” Nephrology Secrets 4th Edition Rockville: Elsevier, 2018: 415-417
- Thomas B, Weir M. “Post-Transplantation Infections.” Nephrology Secrets 4th Edition Rockville: Elsevier, 2018: 418-423
- Thomas B, Weir M. “Primary Care of the Renal Transplant Recipient.” Nephrology Secrets 4th Edition. Rockville: Elsevier, 2018: 424-428
- Thomas B, Weir M. “The Kidney in Rheumatologic Diseases”, Rheumatology 7th Edition. Rockville: Elsevier, 2018:305-316
- Patel A. Thomas B. “Choosing the Best Dialysis Option in the Patient with Acute Kidney Injury and in the Intensive Care Unit.” In: Henrich’s Principles and Practice of Dialysis Fifth Edition. Philadelphia: Wolters Kluwer, 2017: 663-684.
Associate Professor of Clinical Medicine
- Medical Degree: New York University School of Medicine, 1998
- Internship: Beth Israel Deaconess Medical Center, Boston, 1999
- Residency: Beth Israel Deaconess Medical Center, Boston, 2001
- Nephrology Fellowship: Beth Israel Deaconess Medical Center, Boston, 2003
- Transplant Fellowship: Beth Israel Deaconess Medical Center, Boston, 2004
Dr. Gilbert is a transplant nephrologist working in the Medstar Georgetown Transplant Institute and serves as the director of the Transplant Nephrology Fellowship Program. He also developed and now supervises the Transplant Lecture Series for the general nephrology fellows. He has been awarded teacher of the year three times by the division of nephrology and once by the department of medicine. He has been on faculty at Georgetown since 2013 and before that was an attending physician and transplant nephrologist at NYU Langone Medical Center. His clinical work encompasses all phases of transplantation including pre-transplant evaluation, peri-operative management, and post-operative care of transplant patients as well as evaluation of living kidney donors.
He has a special interest and primary role in the use of HIV positive donors as well as cross-blood group transplants from A donors into B or O recipients and is the local P.I. for the HOPE in Action study to more widely use organs from HIV positive donors. He also has an interest in emerging technologies for management of transplant patients including the use of molecular diagnostics to diagnose rejection and using cell-free DNA testing to detect early allograft injury. He regularly mentors fellows and students on research projects in these areas.
In addition to his roles on the transplant candidate selection committee and the living donor selection committee, he served a term as member of the UNOS Kidney Committee developing policy for national kidney allocation. He is a frequent lecturer and has given invited talks at the American Transplant Congress meetings as well as on behalf of the UNOS Minority Affairs Committee and at UNOS regional meetings.
- Gilbert A. Kidney Transplantation across minor ABO incompatibility: the use of A2 to B transplants. Current Opin Organ Transplant 2019 Aug. 24(4): 365-369. PMID 31219841.
- Gilbert A, Grafals M, Timofeeva O, Zaheer M, Karabala A, Rosen-Bronson S, Li D, Awwad M, Abrams P, Moore J, Javaid B, Verbesey J, Ghasemian S, Cooper M. Pre-empting Antibody Mediated Rejection: A Program of DSA Monitoring and Treatment Can Effectively Prevent Antibody Mediated Rejection. Clin Transplant 2016 p.93.
- Yang M, Miller PJ, Case BC, Gilbert AJ, Widell JK, Rogers T, Satler LF, Waksman R, Ben-Dor I. Pre-operative cardiovascular testing and post-renal transplant clinical outcomes. Cardiovasc Revasc Med. 2019 Apr 17. PMID 31097384
- Konkel B, Lavin C, Wu TT, Anderson E, Iwamoto A, Rashid H, Gaitian B, Boone J, Cooper M, Abrams P, Gilbert A, Tang Q, Levi M, Fujimoto JG, Andrews P, Chen Y. Fully automated analysis of OCT imaging of human kidneys for prediction of post-transplant function. Biomed Opt Express 2019 Mar 13; 10(4):1794-1821. PMID: 31086705
- Munjal KG, Wall SP, Goldfrank LR, Gilbert A, Kaufman BJ, Dubler NN; New York City uDCDD Study Group. A rationale in support of uncontrolled donation after circulatory determination of death.
- Hastings Cent Rep. 2013 Jan-Feb;43(1):19-26. doi: 10.1002/hast.113. Epub 2012 Dec 18. PMID: 23254821
- Wall SP, Kaufman BJ, Gilbert AJ, Yushkov Y, Goldstein M, Rivera JE, O’Hara D, Lerner H, Sabeta M, Torres M, Smith CL, Hedrington Z, Selck F, Munjal KG, Machado M, Montella S, Pressman M, Teperman LW, Dubler NN, Goldfrank LR; NYC UDCDD Study Group. Derivation of the uncontrolled donation after circulatory determination of death protocol for New York city. Am J Transplant. 2011 Jul;11(7):1417-26. doi: 10.1111/j.1600-6143.2011.03582.x. Epub 2011 Jun 28. PMID: 21711448
Javaid Basit, MD, MS
Associate Professor of Medicine and Surgery
- MS Epidemiology, Stanford University, 2008-2009
- Fellowship, Stanford University, 1997-2001
- Residency, University of Pennsylvania, Presbyterian Medical Center of Philadelphia, 1994-1997
- Medical School, University of Punjab, Allama Iqbal Medical College, 1985-1990
Dr. Basit Javaid is the medical director of the kidney and pancreas transplant program at MedStar Georgetown Transplant Institute (MGTI), MedStar Georgetown University Hospital, Washington DC. Prior to joining MGTI, Dr. Javaid had worked as a transplant nephrologist at Stanford University, University of Chicago and Penn State University. Dr. Javaid has strong interest in education and has been involved in the education of medical students, residents, and fellows. He has also been involved with multiple clinical trials over his academic career. His clinical focus is to facilitate kidney and pancreas transplantation while ensuring excellent post-transplant outcomes. He has served as reviewer for various journals and has been member of multiple professional organizations including the American College of Physicians, the American Society of Nephrology and the American Society of Transplantation.
- Variability in assessing for BK viremia: whole blood is not reliable and plasma is not above reproach – a retrospective analysis. Agrawal N, Echenique IA, Meehan SM, Limaye AP, Cook L, Chang A, Harland RC, Javaid B, Kadambi PV, Matushek S, Williams J, Josephson MA. Transpl Int. 2017 Jul;30(7):670-678.
- Pre-empting Antibody-Mediated Rejection: A Program of DSA Monitoring and Treatment Can Effectively Prevent Antibody Mediated Rejection. Gilbert A, Grafals M, Timofeeva O, Zaheer M, Karabala A, Rosen-Bronson S, Li D, Awwad M, Abrams P, Moore J, Javaid B, Verbesey J, Ghasemian S, Cooper M. Clin Transpl. 2016;32:93-101.
- BK polyomavirus infection in the renal transplant recipient. Balba GP, Javaid B, Timpone JG Jr. Infect Dis Clin North Am. 2013 Jun;27(2):271-83
- Kidney transplant chains amplify benefit of nondirected donors. Melcher ML, Veale JL, Javaid B, Leeser DB, Davis CL, Hil G, Milner JE. JAMA Surg. 2013 Feb;148(2):165-9
- Preemptive kidney transplantation in systemic lupus erythematosus. Naveed A, Nilubol C, Melancon JK, Girlanda R, Johnson L, Javaid B. Transplant Proc. 2011 Dec;43(10):3713-4.
- Pauci-immune and immune glomerular lesions in kidney transplants for systemic lupus erythematosus. Meehan SM, Chang A, Khurana A, Baliga R, Kadambi PV, Javaid B. Clin J Am Soc Nephrol. 2008 Sep;3(5):1469-78
- The outcome of renal transplantation among systemic lupus erythematosus patients. Chelamcharla M, Javaid B, Baird BC, Goldfarb-Rumyantzev AS. Nephrol Dial Transplant. 2007 Dec;22(12):3623-30.
- Treatment of renal allograft polyoma BK virus infection with leflunomide. Josephson MA, Gillen D, Javaid B, Kadambi P, Meehan S, Foster P, Harland R, Thistlethwaite RJ, Garfinkel M, Atwood W, Jordan J, Sadhu M, Millis MJ, Williams J. Transplantation. 2006 Mar 15;81(5):704-10.
- Polyoma virus infection of renal allografts: relationships of the distribution of viral infection, tubulointerstitial inflammation, and fibrosis suggesting viral interstitial nephritis in untreated disease. Meehan SM, Kadambi PV, Manaligod JR, Williams JW, Josephson MA, Javaid B. Hum Pathol. 2005 Dec;36(12):1256-64.
- Treatment of glomerulonephritis: will we ever have options other than steroids and cytotoxics? Javaid B, Quigg RJ. Kidney Int. 2005 May;67(5):1692-703.
- Leflunomide for polyomavirus type BK nephropathy. Williams JW, Javaid B, Kadambi PV, Gillen D, Harland R, Thistlewaite JR, Garfinkel M, Foster P, Atwood W, Millis JM, Meehan SM, Josephson MA. N Engl J Med. 2005 Mar 17;352(11):1157-8.
- Implications of immunohistochemical detection of C4d along peritubular capillaries in late acute renal allograft rejection. Poduval RD, Kadambi PV, Josephson MA, Cohn RA, Harland RC, Javaid B, Huo D, Manaligod JR, Thistlethwaite JR, Meehan SM. Transplantation. 2005 Jan 27;79(2):228-35.
- Medical School: University of North Carolina Chapel Hill (2006)
- Residency Program: Vanderbilt University Medical Center (2009)
- Fellowship Program: Vanderbilt University Medical Center (2011)
- Transplant Fellowship Program: University of Virginia Medical Center (2012)
Dr. Vranic is an Assistant Professor of Medicine at MedStar Georgetown University Hospital. She completed a fellowship in nephrology at Vanderbilt University, and an additional fellowship in nephrology transplant at UVA. She was previously on faculty at UVA and joined Georgetown in 2017. Her research interests include racial and geographic barriers to renal transplantation, impact of multiple organ transplants on access to transplant, and the role of pre-sensitization in antibody-mediated rejection in renal transplant recipients.
- Birdwell KA, Brady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, Hass DW. The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients. Pharmacogenet Genomics 2012 Jan;22(1):32-42.
- Vranic GM, Ma JZ, Keith DS. The role of minority geographic distribution in waiting time for deceased donor kidney transplantation. Am J Transplant. 2014 Nov;14(11):2526-34. Epub 2014 Aug 25
- Keith DS, Vranic GM. Approach to the Highly Sensitized Kidney Transplant Candidate. Clin J Am Soc Nephrol 2016 Apr 25;11(4):684-93. Epub 2016 Feb 25
- Keith DS, Vranic G, Barcia J, Norwood V, Nishio-Lucar. Longitudinal analysis of living donor kidney transplant rates in pediatric candidates in the United States. Pediatr Transplant 2017 Mar 30;21(2). Epub 2016 Dec 30
Georgetown Research Faculty
Associate Professor of Medicine
- Medical Degree: West China University of Medical Sciences, 1984
- Residency: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, P.R. China, 1988
Dr. Hong Ji has a longstanding interest in the molecular physiology started that at the NIH , after which she joined Georgetown Department of Medicine in 1996. Her interest includes the renin angiotensin aldosterone system in animal models of hypertension and associated vascular and kidney disease, and more recent sex differences in immune modulation of hypertension. Dr Ji’s research expertise lies in cloning, site-directed mutagenesis, mRNA and protein expression, translational regulation, signal transduction, radiotelemetry, renal hemodynamics and mouse breeding and recently with T cell purification and cytokine expression.
Associate Professor of Medicine
- Medical Degree: Gannan Medical College, Jiangxi, China, 1983
- Specialist: Cardiologist, Eleventh Hospital of Wuhan, China, 1990
- PhD: Uppsala University, Uppsala, Sweden, 1990
- Postdoctorate Training: Georgetown University, 2007
- Assistant Professor of Medicine: Georgetown University, 2008
- Associate Professor of Medicine: Georgetown University. 2012
- Distinguished Professor of Medicine: Zhejiang University, China, 2012
Dr. Enyin Lai is an associate professor in the Nephrology and Hypertension division at Georgetown Hospital. His research is focused on measurements of kidney blood flow and glomerular filtration rate (GFR) and the adaptations of the kidney’s microvessels in models of hypertension, chronic kidney disease (CKD), diabetes, cardiovascular disease (CVD), and stroke. He studies directly the afferent and efferent arterioles from mouse kidneys to assess their roles in microvascular remodeling, renal blood flow, autoregulation, vascular reactivity and myogenic responses. He dissects the resistance vessels from the kidneys and the vessels supplying single islets in the pancreas and the vessels in the brain. These are the vessels that determine the function of these three vital organs. He combines these with fluorescence microscopy whose special fluorescent probes to study the generation of key microvascular mediators. These include nitric oxide (NO) and reactive oxygen species (ROS) and intracellular calcium. Some of this studies have focused on the role of an endogenous substance generated in blood vessels termed adenosine. He has defined the receptors on which it acts and its interaction with angiotensin II and nitric oxide. He has shown that this myogenic response of the afferent arteriole is severely impaired in CKD due to generation of hydrogen peroxide. This work is uncovering new therapeutic targets for prevention of kidney damage. Current work entails the isolation and perfusion of micro-cerebral arterioles from the mouse brain and will illuminate the causes and potential solutions to the stroke and neurodegenerative diseases. He has conducted both basic research and translational research with 63 original papers publishes in peer-reviewed journals such as Circulation Research, Hypertension, Diabetes and Kidney International. He is an expert in the renal/cerebral vascular physiology, and molecular cell physiology of vascular endothelial and smooth muscle cells in chronic kidney disease and hypertension.
Assistant Professor of Medicine
- Medical Degree: Wuhan University School of Medicine, Wuhan, China, 1983
- PhD: Uppsala University, Uppsala, Sweden, 2006
- Postdoctoral IRTA Fellow: NIDDK, NIH, 2010
Dr. Li is an assistant professor in the Department of Medicine. She joined Georgetown University in 2011 after extensive training and experience in biomedicine. Her work has been contributed primarily to the multiple completed and ongoing NIH grants. Her special interests include physiology of renal microcirculation, redox regulation of renal arteriolar contractility by using microperfusion techniques, and is currently focusing on the translational research in acute kidney injury and chronic kidney disease.
Professor and Vice Chair for Research, Department of Medicine
Director, Medical CenterDirector, Center for the Study of Sex Differences
Professor, Department of Nephrology & Hypertension
Director, Predoc and Postdoc Training Program in Translational Biomedical Science
- PhD Degree: Biochemistry, University of Maryland, Baltimore 1987
- Postdoctoral Training: Intramural Research Training Award, National Institute of Child Health and Human Development, NIH, 1987-1990
Dr. Kathryn Sandberg is Director of the NIH TL1-funded training program in Translational Biomedical Science for predoctoral students and postdoctoral fellows at Georgetown-Howard Universities Center for Clinical and Translational Science. She is also Professor and Vice Chair for Research in the Department of Medicine and Director of the Center for the Study of Sex Differences in health, aging and disease at Georgetown University. Dr. Sandberg’s laboratory focuses on mechanisms underlying the pathological consequences of blood pressure dysregulation in hypertension, renal disease, anorexia nervosa, aging and in cognitive impairment and dementia. Her laboratory is particularly interested in the role of gonadal steroids, physical activity and the immune and renin angiotensin systems in these pathological mechanisms. Multi-disciplinary approaches to address these questions include studies of angiotensin II metabolism and angiotensin receptor translation, signaling and trafficking using biochemical and molecular techniques and confocal microscopy. The immune system is investigated by flow cytometry in bone marrow transplant and adoptive transfer experiments. Cognitive function is assessed in behavioral studies of rodents and computer tests in humans. Physical activity is measured in rodents using free running wheels and by commercial activity trackers in human participants.
Associate Professor of Medicine
- Medical Degree (M.D): Sun Yat-Sen University of Medical Science, China, 1978-1983,
- Ph.D: Sun Yat-Sen University of Medical Science, China, 1991-1994,
- Postdoctoral Training: Herlev Hospital, Copenhagen University, Copenhagen, Denmark. 1996-2000
- Special Interests: Microvascular physiology in hypertension, chronic kidney disease, aging, HIV-related cardiovascular comorbidity for both basic and clinical/translation research
Dr. Dan Wang serves as an associate professor in the Division of Nephrology and Hypertension, Department of Medicine and leads the Human Hypertension Research Laboratory, which specializes for translational clinical vascular researches. With a longstanding interest in research of microvascular physiology, her current researches focuses on the mechanisms of systemic hypertension and HIV-associated cardiovascular comorbidity. The basic research portion entails studies of oxidative stress related genes, microvascular (mesenteric arterioles) function and therapeutic strategies using rodent models of systemic hypertension and chronic kidney disease. The clinical/translational portion is focused on functional evaluation of living microvessels both ex vivo and in vivo. Approaches include the examination of small human arterioles dissected from a skin biopsy to study the pathogenesis of vascular diseases. In order to better understand mechanisms and be able to follow up the progress of vascular function/remodeling in vascular related diseases, she has established a series of invasive and non-invasive human vascular assessment technologies, including Myography, fluorescent microscopy for ex vivo microvessels; Laser Doppler Flowmetry, iontophresis of vasodilators for in vivo skin blood flow measurement; EndoPAT and capillary digital scope for finger microvascular function and capillary remodeling; Cardio-ankle vascular index and carotid to femoral pulse wave velocity for Conduit arterial function, etc. She is also developing intradermal microdialysis coupled with Laser Doppler flowmetry to further investigate mechanism and therapeutic targets selection of microvascular function in human. Dr. Wang is the principle investigator of an active NIH-RO1 grant titled as “Accelerated aging of microvessels, perivascular adipose tissue in people living with HIV”. She is developing additional research projects, such as “The effect of Pre-exposure prophylaxis (PrEP) on microvascular function in HIV”, “Clinical transnational vascular research program in vascular relation disease” and “Placenta microvascular function in HIV”.
Distinguished Professor of Medicine
- Ph.D: Physiology, University of Kentucky, 1983
- Postdoctoral Training: Hypertension Endocrinology with T.A. Kotchen, MD, 1983-85
Dr. Welch directs the Renal Physiology research laboratory of the Division of Nephrology. His research focuses on the kidney’s ability to maintain fluid and electrolyte balance and how this regulates systemic blood pressure. Renal micropuncture and microperfusion of renal tubules are the main tools used to investigate single nephron function and microcirculatory blood flow. He continues to train post-doctoral fellows in this specialized technique, which historically has provided the most discrete data to identify transport and blood flow function in the kidney. His work is supported by NIH-funded grants, which focus on renal hormones, oxidative stress and oxygen metabolism.
VA Research Faculty
Ping Li, MD, MPH
Associate Professor of Medicine at GWU School of Medicine
Adjunct Assistant Professor of Medicine at MedStar Georgetown University Hospital
- Medical degree: Nei Meng Gu Medical College, 1986
- Research Fellowship: Wake Forest University School of Medicine, 1992
- Internship: Montefiore Medical Center, Albert Einstein College of Medicine,2000
- Residency: Trinitas Hospital and Medical Center. Seton Hall University, 2003
- Fellowship in Nephrology, Georgetown University Hospital, 2008
- MPH: Johns Hopkins University Bloomberg School of Public Health, 2014
Dr. Li is currently a staff nephrologist at the Washington DC Veteran Affair Medical Center and teaching faculty member of Georgetown University and George Washington University.
Dr. Li had extensive hypertension research training on the renin-angiotensin aldosterone system at Wake Forest University and has research and clinical interests in hypertension management. Dr. Li has been an investigator for the SPRINT and CKD BASE trails and is currently participating in hypertension renal denervation clinical trials (SPYRAL HTN-ONMED and TARGETBP I) at the Veterans Affair Medical Center.
- Li P, Chappell MC, Ferrario CM, Brosnihan KB. Angiotensin (1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide. Hypertension. 29 (part 2): 394-400. 1997
- Li P, Ferrario CM, Brosnihan KB. Non-peptide angiotensin II antagonist Losartan inhibits thromboxane A2 induced contractions in canine coronary arteries. Journal of Pharmacology and Experimental Therapeutics. 281:1065-1070, 1997
- Li P, Ferrario CM, and Brosnihan KB. Losartan blocks thromboxane A2 induced platelet aggregation and vascular contractions in spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 32: 198-205, 1998.
- Li P, Fukuhara M, DI Diz, Ferrario CM and Brosnihan KB. Novel AT1 receptor antagonist Irbesartan prevents thromboxane A2-induced vasoconstriction in canine coronary arteries and human platelet aggregation. Journal of Pharmacology and experimental therapeutics. 290(1): 149-54, 2000.
- Li P, Ferrario CM, Ganten D, Brosnihan KB. Chronic estrogen treatment in female transgenic (mRen2) 27 hypertensive rats augments endothelium-derived nitric oxide release. American Journal of Hypertension. 10:662-670, 1997.
- Brosnihan, KB, Li P, Ferrario CM. Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide. Hypertension. 27 (part 2): 523-528. 1996
- Li, P, Houli Jiang, LiMing Yang, Shuo Quan, Sandra Dinocca, Francise Rodriguez, Nader G. Abraham, and Alberto Nasjletti. Angiotensin II Induces Carbon Monoxide Production in the Perfused Kidney: Relation to Protein Kinase C Activation. Am J Physiol (Renal physiol.) 10.1152, 2004
- Li P, Tong C, Eisenach JC, and Figueroa JP. NMDA causes release of nitric oxide from rat spinal cord in vitro. Brain Research. 637:287-291, 1994.
- Li P, Tong C and Eisenach JC. Pregnancy and ephedrine increase release of nitric oxide in ovine uterine arteries. Anesthesia and Analgesia. 82:288-93, 1996.
- Veille JC, Li P, Eisenach JC, Massmann GA, and Figueroa JP. Release, biosynthesis and vasorelaxing activity of nitric oxide in sheep uterine and renal arteries in vitro: influence of estrogen. American Journal of Obstetrics and Gynecology. 174:1043-9, 1996
- Li P, Nader M, Arunagiri K, and Papademetriou V. Device-Based Therapy for Drug-Resistant Hypertension: An Update. Curr. Hypertens. Rep. 18: 64. 2016
- Nader MA, Campos RA, Sharma P, Krishnamoorthy P, Li P, Divino-Fillo J and Lipkowitz, M. In-Hospital Mortality in Cirrhotic Patients with End Stage Renal Disease treated with hemodialysis versus Peritoneal Dialysis: A Nationwide Study. Perit Dial Int., March 27, 2017
- Li P, Nader M, Lessey G and Papademetriou V. Recent advance in Device-Based Therapy for Treatment-Resistant Hypertension. EC Cardiology, 6.5(2019):429-443.
- Palant CE, Chawla LS, Faselis C, Li P, Pallone TL, Kimmel PL, and Amdur RL. High serum creatinine non-linearity: a renal vital sign? Am J Physiol Renal Physiol,311:F305-309; 2016
- Chawla LS, Amdur RL, Faselis C Li, P, Kimmel PA and Plant CE. Impact of Acute Kidney Injury inpatients hospitalized with Pneumonia. Critical Care 2017; 45: 600-606.
- Dobre M, Pajewski N, Beddhu S, Chonchol M, Hostetter, T, Jenkins S, Li P, Rahman M, Servilla K, Yamout H, Weiner d, Wright J, and Raphael K. Serum Bicarbonate and cardiovascular events in high risk hypertensive adults: Results from the Systolic Blood Pressure Intervention Trial. Nephrol Dialysis TransTD 2019,
- Kalani L. Raphael,1 Tamara Isakova,2 Joachim H. Ix,3 Dominic S. Raj,4 Myles Wolf,5 Linda F. Fried,6 Jennifer J. Gassman,7 Cynthia Kendrick,7 Brett Larive,7 Michael F. Flessner,8 Susan R. Mendley,8 John W. Kusek,9 Thomas H. Hostetter,10 Geoffrey A. Block,11 Ping Li,12 John P. Middleton,5 Stuart M. Sprague,13 Donald E. Wesson,14 Alfred K. Cheung1: A randomized trial comparing the safety, adherence and pharmacodynamics profiles of two doses of sodium bicarbonate in CKD: The BASE Pilot Trial. JASN 2020.
Vasilios Papademetriou, MD, DSc, FACC
Director of Hypertension and Interventional Cardiology at the Washington DC VA Medical Center
Associate Professor of Medicine
- Medical Degree: Athens University Medical School, 1974
- Internship: Hellenic Anticancer Institute Athens, Greece, 1975
- Residency: General State Hospital Athens, Greece, 1978
- International Kidney Unit Athens, Greece, 1979
- Dept. of Veterans Affairs Medical Center, Washington, D.C., 1983
- Fellowship: Laboratory of Chemical Pharmacology National Institute of Health, Bethesda, Maryland, 1980
- Fellow in Hypertension, Georgetown University School of Medicine, Veterans Affairs Medical Center, Washington, DC, 1982
- Certifications: Internal Medicine, 1985 ; Cardiology, 1987
Vasilios Papademetriou, MD, is a professor of medicine at Georgetown University School of Medicine, and staff cardiologist at Veterans Affairs Medical Centre in Washington, DC. He is the director of cardiovascular research, interventional hypertension and vascular medicine program, and co-director of the Cardiac Catheterization Laboratory at the Veterans Affairs Medical Centre.
Dr. Papademetriou’ s clinical interests include cardiac catheterization, PCI/STENTS, myocardial biopsies, pericardiocentesis, stress and transesophageal echocardiography, and revascularization of high risk patients. He runs a large clinic of patients with resistant hypertension and dyslipidemia. His research is focused on hypertension and vascular biology, dyslipidemia, atherosclerosis, acute coronary syndromes/acute MI, and cardiovascular complications of diabetes. He has special interest in device-based treatment of patients with resistant hypertension and he is one of the principal investigators of the Renal Denervation projects. He has been a principal investigator for many “investigator initiated” and multicenter clinical trials and received numerous research grants from both public funding and industrial sponsors. Dr. Papademetriou has lectured nationally and internationally for over 20 years.
He has published over 340 peer-reviewed research papers, review articles, editorials, and book chapters and presented over 600 abstracts at national and international meetings . He serves as a reviewer of several prestigious journals such as Circulation, circulation research, JAMA, American Journal of Cardiology, American Heart Journal, American Journal of Hypertension, and the New England Journal of Medicine.
He is a member of many professional societies, and serves as a member of the Joint National Committee on Detection Diagnosis and Treatment of Hypertension and he is a member of the Cardio renal panel of the Food and Drug Administration. He is one of the pioneers of renal denervation
Dr. Papademetriou received his medical degree from Athens University School of Medicine and completed his training at the NIH, Georgetown University and the Department of Veterans Affairs in Washington DC. Dr. Papademetriou is board-certified by the American Board of Internal Medicine and the American Board of Cardiovascular Disease both in the US and in Greece.
Samir Patel, MD
Associate Professor of Medicine at GWU
VAMC Site Director
- Medical Degree: Upstate Medical University, Syracuse 1995
- Residency: The George Washington University, Washington DC 1998 (Internal Medicine)
- Fellowship: The George Washington University, Washington DC 2001 (Nephrology)
Dr. Patel is an Associate Professor of Medicine at the George Washington University and is the section chief of nephrology at the Washington DC Veterans Affairs Medical Center. He was the nephrology Program Director, co-director of the continuous renal replacement program, director of therapeutic apheresis, and director of renal ultrasonography at the George Washington University Medical Center He was elected to AOA as a faculty member in 2007.
His main areas of interest are in chronic kidney disease in the geriatric population, psychosocial issues related to end-stage kidney disease, and medical education. Our second year fellows have the opportunity to participate in clinical research at the VA and he teaches Point of Care Ultrasound for our second year fellows. He has expertise in clinical research and has been a member of the research committee of the National Kidney Foundation for the National Capital Region, and has participated in clinical trials for patients with CKD. He established a clinical research unit at the DC VA Medical Center that has successfully completed a multicenter VA trial testing an antimicrobial agent to prevent dialysis catheter infections. The renal section joined a multicenter trial of palliative care support for late stage and end-stage kidney disease in 2019.
Psychosocial Factors and Patient Care in Kidney Disease
- Patel SS, Shah VS, Peterson RA, Kimmel PL. Psychosocial variables, quality of life, and religious beliefs in ESRD patients treated with hemodialysis. Am J Kidney Dis. 2002 Nov;40(5):1013-22.
- Kimmel PL, Patel SS. Psychosocial issues in women with renal disease. Adv Ren Replace Ther. 2003 Jan;10(1):61-70.
- Patel SS, Peterson RA, Kimmel PL. The Impact of Social Support on End-stage Renal Disease. Seminars in Dialysis 18(2):98-102, 2005
- Patel SS, Holley J. Withholding and Withdrawing Dialysis in the ICU: Benefits Derived from Consulting the RPA/ASN Clinical Practice Guideline, Shared Decision-Making in the Appropriate Initiation of and Withdrawal from Dialysis. Clin J Am Soc Nephrol 2008 3: 587-593.
Impact of Kidney Disease on Quality of Life
- Kimmel PL, Patel SS. Quality of Life in Patients with Chronic Kidney Disease: Focus on End-stage Renal Disease treated with Hemodialysis. Semin Nephrol. 2006 Jan;26(1):68-79.
- Lew SQ, Patel SS. Psychosocial and Quality of Life Issues in Women with End Stage Renal Disease. Advances in Chronic Kidney Diseases 2007; 14(4): 358-363.
- Patel SS. Can we Improve Quality of Life in Hemodialysis Patients?: Treating Pain to Improve Quality of Life in End-Stage Renal Disease. Semin Dial. 2013 Feb 22
Implications of Pain and Sleep in Kidney Disease
- Shyamsunder AK, Patel SS, Jain V, Peterson RA, Kimmel PL. Sleepiness, Sleeplessness, and Pain in End-stage Renal Disease: Distressing Symptoms for Patients. Seminars in Dialysis 2005; 18(2):109-118.
- Cohen SD, Patel SS, Khetpal P, Peterson RA, Kimmel PL. Pain, Sleep Disturbance, and Quality of Life in Patients with Chronic Kidney Disease. Clin J Am Soc Neph. 2007 Sept;2(5):919-925.
- Harris TJ, Nazir R, Khetpal P, Peterson RA, Chava P, Patel SS, Kimmel PL. Pain, Sleep and Survival in Hemodialysis Patients. Nephrol Dial Transplant. 2012 Feb;27(2):758-65.
Contributors to CKD progression and development of End Stage Renal Disease.
- Gollie JM, Harris-Love MO, Patel SS, Argani S: Chronic kidney disease: considerations for monitoring skeletal muscle health and prescribing resistance exercise. Clinical Kidney Journal, 2018 Dec;11(6):822-831
- Palant CE, Patel SS, Chawla LS. Acute Kidney Injury Recovery. Contrib Nephrol. 2018;193:35-44. PMID: 29393153
- Bayoumi E, Lam PH, Dooley DJ, Singh S, Faselis C, Morgan CJ, Patel S, Sheriff HM, Mohammed SF, Palant CE, Pitt B, Fonarow GC, Ahmed A. Spironolactone and Outcomes in Older Patients with Heart Failure and Reduced Ejection Fraction. Am J Med. 2019 Jan;132(1):71-80. PMID: 30240686
- Arundel C, Lam PH, Gill GS, Patel S, Panjrath G, Faselis C, White M, Morgan CJ, Allman RM, Aronow WS, Singh SN, Fonarow GC, Ahmed A. Systolic Blood Pressure and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction. J Am Coll Cardiol. 2019 Jun 25;73(24):3054-3063. doi: 10.1016/j.jacc.2019.04.022. PMID: 31221253.
- Valentova M, Patel S, Lam PH, Faselis C, Arundel C, Fonarow GC, Cheng Y, Allman RM, von Haehling S, Anker SD, Ahmed A. Hypokalaemia and outcomes in older patients hospitalized for heart failure. ESC Heart Fail. 2020 Jun;7(3):794-803. doi: 10.1002/ehf2.12666. Epub 2020 Apr 21. PMID: 32319205
Sharon Bennett, MD
Sholey Argani, MD